The Dog RAB10 ELISA Kit is an innovative tool designed for the detection and quantification of RAB10, a small GTPase protein involved in intracellular vesicle trafficking. This kit is essential for research into cellular transport mechanisms, immune responses, and disease progression in canines. Its applications range from basic biological studies to veterinary diagnostics.
What is RAB10?
RAB10 belongs to the RAB family of GTPases, which regulate vesicle trafficking processes such as endocytosis, exocytosis, and organelle positioning. In dogs, RAB10 is crucial for cellular transport, signal transduction, and maintaining cellular homeostasis. Abnormalities in RAB10 expression are linked to various diseases, including neurological disorders and inflammatory conditions.
For a comprehensive overview of RAB GTPases, visit National Library of Medicine (NLM) and NCBI.
Importance of Studying RAB10 in Dogs
- Neurological Research: RAB10 plays a role in axonal transport and neural function, making it a target for studies on neurodegenerative diseases.
- Learn more at NIH Neuroscience Resources.
- Inflammatory Pathways: Dysregulation of RAB10 can influence immune cell trafficking and inflammatory responses.
- Explore inflammation research at National Institute of Allergy and Infectious Diseases (NIAID).
- Veterinary Diagnostics: RAB10 expression can serve as a biomarker for diseases in dogs, aiding in diagnostics and treatment planning.
- Discover veterinary health tools at USDA Animal Health.
- Comparative Medicine: Studies on canine RAB10 provide insights into similar mechanisms in humans, advancing translational medicine.
- Learn about comparative medicine at NIH Comparative Medicine Resources.
Applications of the Dog RAB10 ELISA Kit
- Disease Biomarker Studies: Facilitates research into conditions such as inflammation, cancer, and neurodegeneration.
- Access biomarker research at NIH Biomarkers.
- Cell Biology Research: Aids in understanding vesicle trafficking and intracellular transport mechanisms.
- Learn about cell biology at American Society for Cell Biology.
- Veterinary Medicine: Enables monitoring of RAB10 levels in dogs for diagnostic and therapeutic purposes.
- Explore veterinary diagnostics at CDC Veterinary Resources.
- Drug Development: Supports preclinical studies by evaluating RAB10-related pathways as potential therapeutic targets.
- Learn about drug development at FDA Veterinary Medicine.
Features of the Dog RAB10 ELISA Kit
- High Sensitivity and Specificity: Designed to detect low levels of RAB10 with minimal cross-reactivity.
- Wide Sample Compatibility: Suitable for serum, plasma, and tissue lysates.
- User-Friendly Protocol: Simplified assay procedure for ease of use.
- Comprehensive Kit: Includes all necessary reagents, standards, and controls.
Protocol and Sample Preparation
The Dog RAB10 ELISA Kit includes detailed instructions for sample collection, preparation, and assay performance. Adhering to these guidelines ensures reliable and reproducible results.
For laboratory best practices, consult resources from the Clinical and Laboratory Standards Institute (CLSI) and CDC Laboratory Standards.
Advancing Research with Trusted Resources
The Dog RAB10 ELISA Kit is a valuable tool for advancing veterinary research and diagnostics. Collaboration between academic and governmental institutions enhances the quality of available tools and data.
- Research Grants: Funding opportunities are available through Grants.gov and the National Science Foundation (NSF).
- Global Health Impact: Understanding RAB10’s role contributes to improving animal and public health.
- Explore global health initiatives at World Health Organization (WHO).
- Comparative Studies: Canine studies provide insights into human diseases, supporting translational research efforts.
- Visit NIH Translational Medicine for more information.
- Public Health: Research on RAB10 in dogs can inform zoonotic disease management.
- Learn about zoonotic diseases at CDC One Health.
Conclusion
The Dog RAB10 ELISA Kit is a versatile and reliable tool for investigating the role of RAB10 in canine health and disease. Its applications in veterinary diagnostics, basic research, and drug development make it indispensable for advancing veterinary and comparative medicine.
For additional technical support and resources, visit PubMed and NIH Research Resources. Trusted resources like FDA Veterinary Medicine and USDA Animal Health Research provide further guidance for conducting high-quality research.
Stay updated on advancements in RAB10 research through reliable sources such as NIH, NIAID, and WHO.